Regulation of cancer stemness by the best combination of nanotech and genetic engineering

The development of chemotherapeutic agents with selective anti-cancer activities is increasingly unattractive due to the emergence of resistance, poor targeting of cancer tissues, and subsequent metastasis. Among tumor characteristic cell types, cancer stem cells are increasingly associated with cancer progression and metastasis, reflecting self-renewal and their propensity to enter the circulation.


Scientists at Japan Advanced Institute of Science and Technology have created a regulation technology of fatal cancer stemness using the combination of nanotechnology and genetic engineering called as "photothermogenetics" that allows for effective cancer elimination.


The present experiments warrant further consideration of this novel chemotherapeutic approach using the best combination of nanotechnology and genetic engineering for the treatment of refractory cancers and control of fatal cancer stemness.



Genetic engineering is an interdisciplinary research subject; its development depends on the development of other basic disciplines including medicine, industry, agriculture and others.


Probe - Research Journal of Genetic Engineering is an international Open Access journal which aims to communicate to its readers, state-of-the-art technologies and methods on Genetic Engineering. It covers all aspects of Genetic Engineering, including Plant and Animal genetics. It accepts original research articles, review articles, case reports and short communications. We sincerely welcome submissions from everyone.

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